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Today, cell line titers, yields and protein concentrations are all increasing. Unfortunately this means there are more cell debris and impurities. Reducing the quantity of these impurities and contaminants earlier in the process is a key requirement for up- and downstream purification processes.

Therefore, you should not miss our Webinar and the Opportunity to learn about a new solution to purify Therapeutic Proteins.

“A New Way to Purify Therapeutic Proteins - Examining case studies for new approaches in combining Ion Exchange Chromatography with Membrane Filtration“

On the 10th of September, 3:00 pm London/10 am New York/16:00 pm Benelux time

Scientific Results will be presented on:

  • New Technology – Emphaze AEX Hybrid Purifier
  • Removing Impurities (HCP, DNA, Viruses, Endotoxins) effectively
  • Removing Host Cell Debris effectively
  • Reducing the Bioburden Level

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  Webinar details

Today, cell line titers, yields and protein concentrations are all increasing. Unfortunately this means there are more cell debris and impurities. In biopharmaceuticals, depth filtration for cell harvesting and clarification is essential to manage high biomass and increasing product concentrations in addition to saving costs in production processes.
The presence of Host Cell Protein, DNA, Endotoxins and Viruses present a high potential risk for biopharmaceutical products. Reducing the quantity of these impurities and contaminants earlier in the process is a key requirement for downstream purification processes. Improvement in purification media performance will contribute to achieving these goals. Scalable single use devices provide the flexibility required in process development and manufacturing facilities.

The webinar focuses on new process strategies that include the protection of sterilizing membranes and chromatography columns in addition to the earlier reduction of impurities (HCP, DNA, Endotoxins, Viruses). 3M Purification introduces the Emphaze AEX Hybrid Purifier.
An overview of the Emphaze design is presented. Potential benefits are discussed, including column protection, reduction of post-capture impurities, and reduction of downstream polishing chromatography needs.

Data from case studies will prove how Emphaze can reach significant results in reducing HCP, DNA and Viruses.

This webinar is essential for every company and process development scientist who needs to improve his biopharmaceutical process economy

Key Learning Objectives

  • New Technology – Emphaze AEX Hybrid Purifier
  • Removing Impurities (HCP, DNA, Viruses, Endotoxins) effectively
  • Removing Host Cell Debris effectively
  • Reducing the Bioburden Level

 Presentation by Dr. Sophie Winterfeld

Dr. Sophie Winterfeld
Senior Engineer Application Development
for Purification in Life Sciences

Dr. Sophie Winterfeld studied Biochemistry at the Martin-Luther-University Halle-Wittenberg with focus on Protein Chemistry. She graduated at the University of Hohenheim Stuttgart with focus on Protein Chemistry. Since August 2012 she works as Application Specialist for 3M Purification and has experience in custom-built filtration application development in the Biotech and Pharmaceutical Industry.

 

 

23/07/2013

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